This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to determine if the presence of an asymptomatic antenatal nuchal cord has clinical significance and, if so, are ancillary findings of any potential value in formulating a management plan. Nuchal cords during labor are associated with fetal distress and poor outcomes in some cases. The true incidence of nuchal cords during pregnancy and labor, and the outcome of infants with nuchal cords at these times is unknown. Each pregnant woman will be studied at 24-26 weeks, 30-32 weeks, 36-38 weeks, and labor. Specific antenatal measurements include ultrasonic detection of a nuchal cord, non-stress test, biophysical profile and vecilometry of the umbilical and brain circulation. Follow-up studies will be done in the infants at five days and one year of life and include morphometric and neurodevelopmental parameters. The presence of nuchal cord will be correlated with biophysical testing at that time and outcomes in the infant (growth, head ultrasound, and Bayley scores).
Showing the most recent 10 out of 753 publications