Abstract

Differences in methionine metabolism(transmethylation, remethylation & transsulfuration) may be observed in these subject groups during a primed constant infusion study using the stable isotope L-2H3-methyl-1-13C- methionine. Simultaneous infusion with labeled cysteine may give further information about transsulfuration. Studies giving the stable isotope tracers orally will help define whether TPN patients are also at risk for disturbed methionine metabolism when this amino acid is given parenterally versus enterally.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR000088-29
Application #
3849367
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
29
Fiscal Year
1992
Total Cost
Indirect Cost

  Institution

Name
Massachusetts Institute of Technology
Department
Type
DUNS #
City
Cambridge
State
MA
Country
United States
Zip Code
02139

  Publications

Raboud, Janet M; Diong, Christina; Carr, Andrew et al. (2010) A meta-analysis of six placebo-controlled trials of thiazolidinedione therapy for HIV lipoatrophy. HIV Clin Trials 11:39-50
Must, Aviva; Bandini, Linda G; Tybor, David J et al. (2008) Behavioral risk factors in relation to visceral adipose tissue deposition in adolescent females. Int J Pediatr Obes 3 Suppl 1:28-36
Bandini, L G; Must, A; Naumova, E N et al. (2008) Change in leptin, body composition and other hormones around menarche--a visual representation. Acta Paediatr 97:1454-9
Thadhani, Ravi (2008) Activated vitamin D sterols in kidney disease. Lancet 371:542-4
Must, Aviva; Bandini, Linda G; Tybor, David J et al. (2007) Activity, inactivity, and screen time in relation to weight and fatness over adolescence in girls. Obesity (Silver Spring) 15:1774-81
Thompson, O M; Ballew, C; Resnicow, K et al. (2006) Dietary pattern as a predictor of change in BMI z-score among girls. Int J Obes (Lond) 30:176-82
Spadano, Jennifer L; Bandini, Linda G; Must, Aviva et al. (2005) Longitudinal changes in energy expenditure in girls from late childhood through midadolescence. Am J Clin Nutr 81:1102-9
Anderson, S E; Bandini, L G; Must, A (2005) Child temperament does not predict adolescent body composition in girls. Int J Obes (Lond) 29:47-53
Schurgin, Sunita; Dolan, Sara; Perlstein, Ari et al. (2004) Effects of testosterone administration on growth hormone pulse dynamics in human immunodeficiency virus-infected women. J Clin Endocrinol Metab 89:3290-7
Bandini, Linda G; Must, Aviva; Phillips, Sarah M et al. (2004) Relation of body mass index and body fatness to energy expenditure: longitudinal changes from preadolescence through adolescence. Am J Clin Nutr 80:1262-9

Showing the most recent 10 out of 144 publications