Indirect calorimetry and stable isotope technique will be used to investigate the progressive (temporal) alterations in lipid, glucose and protein metabolism during short-term fasting in young women and men, who meet the military body-weight and percent body-fat standards. Moreover we will test the hypothesis that a prior high intake of protein (2.5 g/kg-1/day-1) modifies the metablolic response to a short-term (3 day) fast, with preferential sparing of body protein in both women and men.

Project Start
1998-12-01
Project End
1999-11-30
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
36
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Massachusetts Institute of Technology
Department
Type
DUNS #
City
Cambridge
State
MA
Country
United States
Zip Code
02139
Raboud, Janet M; Diong, Christina; Carr, Andrew et al. (2010) A meta-analysis of six placebo-controlled trials of thiazolidinedione therapy for HIV lipoatrophy. HIV Clin Trials 11:39-50
Must, Aviva; Bandini, Linda G; Tybor, David J et al. (2008) Behavioral risk factors in relation to visceral adipose tissue deposition in adolescent females. Int J Pediatr Obes 3 Suppl 1:28-36
Bandini, L G; Must, A; Naumova, E N et al. (2008) Change in leptin, body composition and other hormones around menarche--a visual representation. Acta Paediatr 97:1454-9
Thadhani, Ravi (2008) Activated vitamin D sterols in kidney disease. Lancet 371:542-4
Must, Aviva; Bandini, Linda G; Tybor, David J et al. (2007) Activity, inactivity, and screen time in relation to weight and fatness over adolescence in girls. Obesity (Silver Spring) 15:1774-81
Thompson, O M; Ballew, C; Resnicow, K et al. (2006) Dietary pattern as a predictor of change in BMI z-score among girls. Int J Obes (Lond) 30:176-82
Spadano, Jennifer L; Bandini, Linda G; Must, Aviva et al. (2005) Longitudinal changes in energy expenditure in girls from late childhood through midadolescence. Am J Clin Nutr 81:1102-9
Anderson, S E; Bandini, L G; Must, A (2005) Child temperament does not predict adolescent body composition in girls. Int J Obes (Lond) 29:47-53
Spadano, Jennifer L; Bandini, Linda G; Must, Aviva et al. (2004) Does menarche mark a period of elevated resting metabolic rate? Am J Physiol Endocrinol Metab 286:E456-62
Anderson, S E; Bandini, L G; Dietz, W H et al. (2004) Relationship between temperament, nonresting energy expenditure, body composition, and physical activity in girls. Int J Obes Relat Metab Disord 28:300-6

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