Abstract

To compare carbohydrate-rich and protein-rich weight reduction plans on the long-term efficacy of Dexfenfluramine on weight loss. Subjects are to be treated with Redux for 12 months and consume twice daily a high carbohydrate beverage designed to increase brain tryptophan uptake or consume a control, protein-rich beverage that will inhibit brain tryptophan uptake. Weight loss will be monitored for 12 months.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
3M01RR000088-37S1
Application #
6439591
Study Section
Project Start
1999-12-01
Project End
2001-11-30
Budget Start
Budget End
Support Year
37
Fiscal Year
2001
Total Cost
Indirect Cost

  Institution

Name
Massachusetts Institute of Technology
Department
Type
DUNS #
City
Cambridge
State
MA
Country
United States
Zip Code
02139

  Publications

Raboud, Janet M; Diong, Christina; Carr, Andrew et al. (2010) A meta-analysis of six placebo-controlled trials of thiazolidinedione therapy for HIV lipoatrophy. HIV Clin Trials 11:39-50
Must, Aviva; Bandini, Linda G; Tybor, David J et al. (2008) Behavioral risk factors in relation to visceral adipose tissue deposition in adolescent females. Int J Pediatr Obes 3 Suppl 1:28-36
Bandini, L G; Must, A; Naumova, E N et al. (2008) Change in leptin, body composition and other hormones around menarche--a visual representation. Acta Paediatr 97:1454-9
Thadhani, Ravi (2008) Activated vitamin D sterols in kidney disease. Lancet 371:542-4
Must, Aviva; Bandini, Linda G; Tybor, David J et al. (2007) Activity, inactivity, and screen time in relation to weight and fatness over adolescence in girls. Obesity (Silver Spring) 15:1774-81
Thompson, O M; Ballew, C; Resnicow, K et al. (2006) Dietary pattern as a predictor of change in BMI z-score among girls. Int J Obes (Lond) 30:176-82
Anderson, S E; Bandini, L G; Must, A (2005) Child temperament does not predict adolescent body composition in girls. Int J Obes (Lond) 29:47-53
Spadano, Jennifer L; Bandini, Linda G; Must, Aviva et al. (2005) Longitudinal changes in energy expenditure in girls from late childhood through midadolescence. Am J Clin Nutr 81:1102-9
Koutkia, Polyxeni; Canavan, Bridget; Breu, Jeff et al. (2004) Nocturnal ghrelin pulsatility and response to growth hormone secretagogues in healthy men. Am J Physiol Endocrinol Metab 287:E506-12
Schurgin, Sunita; Dolan, Sara; Perlstein, Ari et al. (2004) Effects of testosterone administration on growth hormone pulse dynamics in human immunodeficiency virus-infected women. J Clin Endocrinol Metab 89:3290-7

Showing the most recent 10 out of 144 publications