This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Brandykinin 1-5, the vivo metabolite of brandykinin in humans, is vasoactive.
Specific aim : To determine if BK1-5 causes vasodilation in the human forearm vasculature. To determine if BK1-5 induces t-PA release from the forearm vascular endothelium.
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