This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. 1.) Subjects with variant of OATP-C transporter will have altered pravastatin disposition profiles. 2.) Prevalence and types of variant OATP-C transporter will be associated with ethnic differences in the disposition of pravastatin.
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