This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Hypothesis and Specific AimsTo test the hypothesis that angiotensin II induces oxidation and inflammation in humans through endogenous aldosterone, and that this effect can be blocked by aldosterone receptor antagonism.
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