This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.Hypothesis 1 In older adults with epilepsy, obstructive sleep apnea (OSA) is more common in those with new-onset seizures or worsening seizures compared to those with well-controlled seizures.
Specific Aim 1 All patients with epilepsy ages 50 years and older who are capable of tolerating polysomnography will be invited to participate in comprehensive polysomnography in the Vanderbilt General Clinical Research Center (GCRC). These patients will be recruited from those presenting to the emergency department for evaluation of new-onset or worsening seizure frequency as well as the neurology clinic and the epilepsy monitoring unit.Hypothesis 2 The Sleep Apnea Scale of the Sleep Disorders Questionnaire (SA-SDQ) is a useful screening instrument for OSA in older adults with epilepsy.
Specific Aim 2 Administer the SA-SDQ to the group identified above. Determine its sensitivity and specificity in predicting OSA in this population.
Showing the most recent 10 out of 515 publications
