This study will determine if there are increased numbers of activated alveolar macrophages in individuals with radiographic abnormalities consistent with their asbestos exposure that release increased quantities of peptide growth factors that signal mesenchymal cells to proliferate. The investigators will measure macrophage growth factors at the mRNA level to evaluate gene expression and macrophage supernatants to quantitate spontaneous protein release. The study will evaluate six known growth factors.

Project Start
Project End
Budget Start
Budget End
Support Year
32
Fiscal Year
1993
Total Cost
Indirect Cost
Name
New York University
Department
Type
DUNS #
004514360
City
New York
State
NY
Country
United States
Zip Code
10012
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