Tamoxifen has been found to reduce the incidence of breast cancer in women at increased risk, but has some troublesome side effects. It is FDA-approved for this indication. Raloxifene has been FDA-approved for the prevention of osteoporosis. Raloxifene may also reduce the risk of devloping breast cancer with fewer side effects than tamoxifen. This randomized, double-blind study will determine if raloxifene is either more or less effective than tamoxifen in reducing the incidence of invasive breast cancer in postmenopausal women who are at increased risk for the disease. A secondary goal is to determine whether raloxifene reduces the endometrial cancer rate as compared to tamoxifen.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR000096-39
Application #
6412523
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
1975-10-01
Project End
2003-11-30
Budget Start
Budget End
Support Year
39
Fiscal Year
2000
Total Cost
Indirect Cost
Name
New York University
Department
Type
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10016
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