This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This project seeks to establish a comprehensive medical screening program to provide medical assessments, diagnostic referrals and occupational health education for rescue, recovery, volunteer and other works exposed to the World Trade Center (WTC) site after the 9/11 tragedy. The goals of the project are to: 1) identify individuals exposed to the WTC site; 2) provide clinical assessment and identify those with persistent medical problems; 3) coordinate referral for follow-up clinical care; 4) educate subjects about possible exposures and their health effects; 5) provide baseline clinical status for individuals exposed at or near ground zero. This proposal clearly addresses an important problem, namely the health status of individuals at or near ground zero. The study design consists of a single outpatient health assessment with routine physical exam, blood work and pulmonary function tests. Any abnormalities will be reported to the patient for potential follow-up. The study is funded by the CDC/NIOSH and will be primarily administered by the Mount Sinai Center for Occupational and Environmental Medicine. A total of 8500 individuals will be enrolled and of these 200 will be enrolled at this site and use the GCRC. Data will be evaluated by simple descriptive statistics. To date, up to 50% of patients enrolled in the study have shown upper respiratory symptoms and abnormal pulmonary function tests after exposure to the WTC
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