Patients screened for HDL cholesterol, apo A-I and apo A-II levels. HDL turnover is assessed in vivo to determine synthetic and catabolic rate of HDL apolipoproteins. Nutritional perturbations of HDL metabolism are assessed by studying patients on low and high fat diets. The influence of alcohol on HDL metabolism is also under study. Genetic regulation of HDL metabolism is being assessed by performing HDL turnover studies in twins.

Project Start
Project End
Budget Start
Budget End
Support Year
30
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Rockefeller University
Department
Type
DUNS #
071037113
City
New York
State
NY
Country
United States
Zip Code
10065
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