Production of critical cytokines by T-cells and other host cells, especially monocytes, mediates resistance and susceptibility to infectious agents. We are testing two doses of the drug thalidomide in a placebo-controlled clinical trial in patients with HIV associated wasting. We hope to reduce the production of TNFa and thereby reduce wasting, fevers and the production of the virus.

Project Start
Project End
Budget Start
Budget End
Support Year
32
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Rockefeller University
Department
Type
DUNS #
071037113
City
New York
State
NY
Country
United States
Zip Code
10065
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