The overall goal of the General Clinical Research Center (GCRC) at Baylor College of Medicine is to provide an environment for patient-oriented research which leads to an improved understanding of various disease processes, allows for better methods of treatment and diagnosis, offers training for clinical investigators, and facilitates the collaboration of investigators conducting clinical research. The GCRC supports studies ranging from Pediatrics, Medicine, Allergy/Immunology, Genetics, Obstetrics and Gynecology, Surgery, Neonatology, Cell and Gene Therapy, Hematology/Oncology, Endocrinology, Infectious Disease, Neurology, Gastroenterology, and Nutrition. Each protocol submission must have IRB approval and undergo a review by the GCRC Scientific Advisory Committee focusing on scientific merit, study design, analysis and patient safety. Once approved by the Committee, an investigator can utilize the GCRC and its resources. The General Clinical Research Center at Baylor College of Medicine has been open at Texas Children's Hospital and supported through the NCRR at NIH for 41 years. The GCRC is structured to accommodate patient-oriented research activities at appropriate sites throughout various departments of Baylor College of Medicine. A single administrative structure supports both the Pediatric and Adult Units of the GCRC. The Pediatric Unit at Texas Children's Hospital includes a discrete inpatient unit consisting of six patient beds, an outpatient clinic, specialized Neonatal Research Satellite Unit located within the neonatal intensive care unit, as well as a gene therapy core laboratory available to both the pediatric and adult units. The Adult Satellite Unit consists of a per diem unit within The Methodist Hospital as well as adult outpatient facilities located on the 12th floor of the Baylor Clinic building.

National Institute of Health (NIH)
National Center for Research Resources (NCRR)
General Clinical Research Centers Program (M01)
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National Center for Research Resources Initial Review Group (RIRG)
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Merchant, Carol
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Baylor College of Medicine
Schools of Medicine
United States
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Hunsaker, Sanita L; Garland, Beth H; Rofey, Dana et al. (2018) A Multisite 2-Year Follow Up of Psychopathology Prevalence, Predictors, and Correlates Among Adolescents Who Did or Did Not Undergo Weight Loss Surgery. J Adolesc Health 63:142-150
Lanzieri, Tatiana M; Chung, Winnie; Leung, Jessica et al. (2018) Hearing Trajectory in Children with Congenital Cytomegalovirus Infection. Otolaryngol Head Neck Surg 158:736-744
Bollard, Catherine M; Tripic, Tamara; Cruz, Conrad Russell et al. (2018) Tumor-Specific T-Cells Engineered to Overcome Tumor Immune Evasion Induce Clinical Responses in Patients With Relapsed Hodgkin Lymphoma. J Clin Oncol 36:1128-1139
Michalsky, Marc P; Inge, Thomas H; Jenkins, Todd M et al. (2018) Cardiovascular Risk Factors After Adolescent Bariatric Surgery. Pediatrics 141:
Lau, Chantal (2018) Breastfeeding Challenges and the Preterm Mother-Infant Dyad: A Conceptual Model. Breastfeed Med 13:8-17
Jenkins, Todd M; Boyce, Tawny W; Ralph Buncher, C et al. (2017) Accuracy of Self-Reported Weight Among Adolescent and Young Adults Following Bariatric Surgery. Obes Surg 27:1529-1532
Cao, Felicia; Lu, Linchao; Abrams, Steven A et al. (2017) Generalized metabolic bone disease and fracture risk in Rothmund-Thomson syndrome. Hum Mol Genet 26:3046-3055
Wattacheril, Julia; Lavine, Joel E; Chalasani, Naga P et al. (2017) Genome-Wide Associations Related to Hepatic Histology in Nonalcoholic Fatty Liver Disease in Hispanic Boys. J Pediatr 190:100-107.e2
El-Hattab, Ayman W; Almannai, Mohammed; Scaglia, Fernando (2017) Arginine and citrulline for the treatment of MELAS syndrome. J Inborn Errors Metab Screen 5:
Lanzieri, Tatiana M; Chung, Winnie; Flores, Marily et al. (2017) Hearing Loss in Children With Asymptomatic Congenital Cytomegalovirus Infection. Pediatrics 139:

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