Abstract

The aims of the study are 1)to perform pancreas transplants from cadeveric donors of Type I diabetics and to study this form of therapy for complicated Type I diabetes, 2)to study endocrine function of the pancreas grafts in terms of insulin secretory capacity and associated metabolic parameters and 3)to study the effects of pancreas transplantation on the chronic target organ complications of diabetes.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR000211-32
Application #
5220123
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
32
Fiscal Year
1996
Total Cost
Indirect Cost

  Publications

Nyenwe, Ebenezer; Owei, Ibiye; Wan, Jim et al. (2018) Parental History of Type 2 Diabetes Abrogates Ethnic Disparities in Key Glucoregulatory Indices. J Clin Endocrinol Metab 103:514-522
Messier, Stephen P; Resnik, Allison E; Beavers, Daniel P et al. (2018) Intentional Weight Loss in Overweight and Obese Patients With Knee Osteoarthritis: Is More Better? Arthritis Care Res (Hoboken) 70:1569-1575
Sanders, John T; Hastings, M Colleen; Moldoveanu, Zina et al. (2017) Serial Galactose-Deficient IgA1 Levels in Children with IgA Nephropathy and Healthy Controls. Int J Nephrol 2017:8210641
Pogacnik Murillo, Aarón Leonardo; Eckstein, Felix; Wirth, Wolfgang et al. (2017) Impact of Diet and/or Exercise Intervention on Infrapatellar Fat Pad Morphology: Secondary Analysis from the Intensive Diet and Exercise for Arthritis (IDEA) Trial. Cells Tissues Organs 203:258-266
Messier, S P; Beavers, D P; Herman, C et al. (2016) Are unilateral and bilateral knee osteoarthritis patients unique subsets of knee osteoarthritis? A biomechanical perspective. Osteoarthritis Cartilage 24:807-13
Boucher, Andrew B; Adesanya, E A Omoluyi; Owei, Ibiye et al. (2015) Dietary habits and leisure-time physical activity in relation to adiposity, dyslipidemia, and incident dysglycemia in the pathobiology of prediabetes in a biracial cohort study. Metabolism 64:1060-7
Hunter, D J; Beavers, D P; Eckstein, F et al. (2015) The Intensive Diet and Exercise for Arthritis (IDEA) trial: 18-month radiographic and MRI outcomes. Osteoarthritis Cartilage 23:1090-8
Ebenibo, Sotonte; Edeoga, Chimaroke; Wan, Jim et al. (2014) Glucoregulatory function among African Americans and European Americans with normal or pre-diabetic hemoglobin A1c levels. Metabolism 63:767-72
Dagogo-Jack, Samuel; Edeoga, Chimaroke; Ebenibo, Sotonte et al. (2014) Lack of racial disparity in incident prediabetes and glycemic progression among black and white offspring of parents with type 2 diabetes: the pathobiology of prediabetes in a biracial cohort (POP-ABC) study. J Clin Endocrinol Metab 99:E1078-87
Messier, S P; Pater, M; Beavers, D P et al. (2014) Influences of alignment and obesity on knee joint loading in osteoarthritic gait. Osteoarthritis Cartilage 22:912-7

Showing the most recent 10 out of 185 publications