This study ascertains the caloric (energy) and protein needs of MSUD patients by age, sex, body composition, growth, nutritional status and physical activity using available technological advances in determination of total and resting energy expenditure using stable isotope techniques and indirect calorimetry together with a newly validated method for determining lean body mass and body fat.

Project Start
Project End
Budget Start
Budget End
Support Year
26
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Children's Hospital of Philadelphia
Department
Type
DUNS #
073757627
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
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Medina-Gómez, Carolina; Chesi, Alessandra; Heppe, Denise H M et al. (2015) BMD Loci Contribute to Ethnic and Developmental Differences in Skeletal Fragility across Populations: Assessment of Evolutionary Selection Pressures. Mol Biol Evol 32:2961-72
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