Buserelin is a long-acting luteinizing hormone releasing hormone (LHRH). This study is to test the effectiveness of this new drug in the treatment of children with precocious puberty (development of secondary sexual characteristics at an inappropriate early age). These children often end up with extreme short stature because of cessation of growth after sexual development. The efficacy of this new drug in treating precocious puberty was evaluated clinically, biochemically, and radiologically.

Project Start
Project End
Budget Start
Budget End
Support Year
28
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Children's Hospital of Philadelphia
Department
Type
DUNS #
073757627
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
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Rutstein, Richard M; Samson, Pearl; Fenton, Terry et al. (2015) Long-term safety and efficacy of atazanavir-based therapy in HIV-infected infants, children and adolescents: the Pediatric AIDS Clinical Trials Group Protocol 1020A. Pediatr Infect Dis J 34:162-7
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