The purpose of this study is to examine the effect of alcohol abuse on the production of melatonin from the pineal gland as evidenced by the development of chronobiologic sleep and mood disorders. Little is known about the effect of alcohol abuse on the function of the human pineal gland, but several recently published studies suggest that alcohol abuse adversely affects pineal gland function. Ethanol may directly affect pinealocytes by inhibiting the normal circandian rhythm of melatonin production.

Project Start
Project End
Budget Start
Budget End
Support Year
29
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Oregon Health and Science University
Department
Type
DUNS #
009584210
City
Portland
State
OR
Country
United States
Zip Code
97239
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