This study will evaluate the hypocholesterolemic effects and influence on cholesterol biosynthesis of simvastatin and fluvastatin in 25-30 patients with moderate primary hypercholesterolemia. After a five week dietary baseline, patients will receive active drug therapy with three potential doses of simvastatin (5, 10, or 20 mg/day) or fluvastatin (20 or 40 mg/day). Patients will receive three of these five treatment options each for a period of five weeks.

Project Start
Project End
Budget Start
Budget End
Support Year
29
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Oregon Health and Science University
Department
Type
DUNS #
009584210
City
Portland
State
OR
Country
United States
Zip Code
97239
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