The primary goal of this pilot study is the generation of pharmacokinetic profiles (oral bioavailability) - F, and metabolic clearance -CLt, in particular) of 2 distinct racial patient groups awaiting renal transplantation: caucasian and african americans. The secondary goal would be to establish a tacrolimus pharmacokinetic profile database where data from all types of organ transplant recipients can be utilized to provide a more effective set of guidelines for use of tacrolimus blood levels to aid optimization of dosing of the drug.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
2M01RR000349-31A1
Application #
6278211
Study Section
Project Start
1998-09-15
Project End
1998-11-30
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
31
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Temple University
Department
Type
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
19122
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