It is known that human neoplasms produce a variety of hormone-like factors which cause hypercalcemia and/or hypercalciuria. This cytokine- induced mechanism occurs in both solid tumors and lymphoproliferative neoplasms. This project will gain a better understanding of the pathophysiology of this finding in patients with lymphoma and leukemia which results form the dysregulated overproduction of an active vitamin D.
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