This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Varicella-Zoster virus infection is usually benign in normal children. It can be devastating in HIV infected children. HIV infected children are subject to repeated injections of VZIG. This study will test the ability of children with early and mild HIV infection to respond to the vaccine and measure the safety and duration of immunity achieved in immunized children.
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