This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This project is the initial segment of a two-part study. We will screen high-risk participants with an oral glucose tolerance test. The individuals with normal glucose tolerance will be asked to participate in our other GCRC SPID 0646. The individuals with impaired glucose tolerance will be asked to participate in this project. The primary objective of this investigation is to determine whether the improvement of insulin sensitivity following treatment with a thiazolidine drug is associated with reduced lipid stores in cardiac and skeletal muscle in individuals with impaired glucose tolerance. This study has received an exemption for IND from the FDA.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR000633-34
Application #
7377605
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
2006-04-01
Project End
2007-03-31
Budget Start
2006-04-01
Budget End
2007-03-31
Support Year
34
Fiscal Year
2006
Total Cost
$38,966
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
800771545
City
Dallas
State
TX
Country
United States
Zip Code
75390
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