EXCEED THE SPACE PROVIDED. The General Clinical Research Center (GCRC) at the University of California San Diego (UCSD) supports faculty investigators throughout the School of Medicine in their pursuit of clinical studies judged scientifically meritorious by the GCRC Advisory Committee and approved by the UCSD Human Research Protection Program. Major areas of investigation include diabetes, pediatric metabolic errors, physiology of sex hormones, pathophysiology of endocrine dysfunction, blood pressure control, hyperlipidemia and heart disease, sleep physiology and neurochemistry, infectious diseases, pulmonary diseases and cancer treatment. Resources include 8 inpatient beds at the UCSD Medical Center with adjacent Metabolic Kitchen, Informatics Core for biostatistical and computer support, two outpatient rooms and administrative support space. A 1100 sq. ft. Core Laboratory is located across the street in the Clinical Teaching Facility. In addition to the facilities at the Medical Center campus in Hillcrest, an outpatient facility encompassing approximately 3000 sq. ft. has been operational since 1984 on the La Jolla campus. As a result of the 15 mile distance between the two campuses, a supplemental application to fund scatter beds at the VA Medical Center adjacent to the La Jolla campus was funded in 1987 to meet the inpatient needs of investigators located on the La Jolla campus. In April 2000, a satellite facility was funded and opened at the University of California Irvine with outpatient resources and a Specialized Human

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
2M01RR000827-31
Application #
6956524
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Program Officer
Merchant, Carol
Project Start
1997-01-27
Project End
2010-11-30
Budget Start
2006-04-01
Budget End
2006-11-30
Support Year
31
Fiscal Year
2006
Total Cost
$6,153,300
Indirect Cost
Name
University of California San Diego
Department
Type
Schools of Medicine
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Grams, Morgan E; Sang, Yingying; Ballew, Shoshana H et al. (2018) Predicting timing of clinical outcomes in patients with chronic kidney disease and severely decreased glomerular filtration rate. Kidney Int 93:1442-1451
Lavigne, Katie M; Woodward, Todd S (2018) Hallucination- and speech-specific hypercoupling in frontotemporal auditory and language networks in schizophrenia using combined task-based fMRI data: An fBIRN study. Hum Brain Mapp 39:1582-1595
Milot, Marie-Hélène; Marchal-Crespo, Laura; Beaulieu, Louis-David et al. (2018) Neural circuits activated by error amplification and haptic guidance training techniques during performance of a timing-based motor task by healthy individuals. Exp Brain Res 236:3085-3099
Hsu, Simon; Rifkin, Dena E; Criqui, Michael H et al. (2018) Relationship of femoral artery ultrasound measures of atherosclerosis with chronic kidney disease. J Vasc Surg 67:1855-1863.e1
Inker, Lesley A; Grams, Morgan E; Levey, Andrew S et al. (2018) Relationship of Estimated GFR and Albuminuria to Concurrent Laboratory Abnormalities: An Individual Participant Data Meta-analysis in a Global Consortium. Am J Kidney Dis :
Egnot, Natalie Suder; Barinas-Mitchell, Emma; Criqui, Michael H et al. (2018) An exploratory factor analysis of inflammatory and coagulation markers associated with femoral artery atherosclerosis in the San Diego Population Study. Thromb Res 164:9-14
Juraschek, Stephen P; Miller 3rd, Edgar R; Appel, Lawrence J (2018) Orthostatic Hypotension and Symptoms in the AASK Trial. Am J Hypertens 31:665-671
Chen, Teresa K; Appel, Lawrence J; Grams, Morgan E et al. (2017) APOL1 Risk Variants and Cardiovascular Disease: Results From the AASK (African American Study of Kidney Disease and Hypertension). Arterioscler Thromb Vasc Biol 37:1765-1769
Juraschek, Stephen P; Appel, Lawrence J; Miller 3rd, Edgar R (2017) Metoprolol Increases Uric Acid and Risk of Gout in African Americans With Chronic Kidney Disease Attributed to Hypertension. Am J Hypertens 30:871-875
Chen, Teresa K; Tin, Adrienne; Peralta, Carmen A et al. (2017) APOL1 Risk Variants, Incident Proteinuria, and Subsequent eGFR Decline in Blacks with Hypertension-Attributed CKD. Clin J Am Soc Nephrol 12:1771-1777

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