The purpose of this protocol is to establish the qualitative and quantitative toxicity of bryostatin 1 when administered to children whose cancer is refractory to standard therapy. This study will determine dose-limiting toxicities, establish a maximum tolerated dose and obtain pharmacokinetic data. This study will provide information to determine which clinical and laboratory studies are needed to monitor or alter therapy with this agent and to determine precautions and supportive therapy that should be used. New protocol.

Project Start
Project End
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
25
Fiscal Year
1998
Total Cost
Indirect Cost
Name
University of Virginia
Department
Type
DUNS #
001910777
City
Charlottesville
State
VA
Country
United States
Zip Code
22904
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