This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.We propose, in this study, to observe the reorganization of the central nervous system visual and auditory processing areas during adaptation to a visually inverted world. While the behavioral characteristics of this adaption have been characterized well over the past 100 years, the neural plasticity likely to underlie the adaptation is understood poorly in humans. Modern fMRI presents us with the unique and important opportunity to observe functional reorganization in different areas of the human brain noninvasively druing and after such large-scale adaptation.
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