This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator.
SPECIFIC AIMS : The primary goal of this study is to determine if Fish Oil reduces seizures and the risk of cardiac arrhythmias in people with epilepsy. This fundamental hypothesis will be addressed in a pilot clinical trial, which explores the following two specific aims:
Specific Aim 1 : To obtain preliminary data regarding the safety and effectiveness of Fish Oil compared with placebo in reducing seizure frequency in adults with intractable epilepsy. Hypothesis 1a. Fish Oil is safe and well tolerated in subjects with epilepsy. Hypothesis 1b. Seizure frequency and severity is reduced during active treatment with Fish Oil compared with placebo. Hypothesis 1c. Levels of the N-3 fatty acids, EPA and DHA, rise significantly in epileptic patients after supplementation, and are correlated with response.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR000865-37
Application #
8167086
Study Section
Special Emphasis Panel (ZRR1-CR-4 (01))
Project Start
2009-12-01
Project End
2010-11-30
Budget Start
2009-12-01
Budget End
2010-11-30
Support Year
37
Fiscal Year
2010
Total Cost
$42,851
Indirect Cost
Name
University of California Los Angeles
Department
Type
Schools of Medicine
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
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