This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator.
SPECIFIC AIMS : The primary goal of this study is to determine if Fish Oil reduces seizures and the risk of cardiac arrhythmias in people with epilepsy. This fundamental hypothesis will be addressed in a pilot clinical trial, which explores the following two specific aims:
Specific Aim 1 : To obtain preliminary data regarding the safety and effectiveness of Fish Oil compared with placebo in reducing seizure frequency in adults with intractable epilepsy. Hypothesis 1a. Fish Oil is safe and well tolerated in subjects with epilepsy. Hypothesis 1b. Seizure frequency and severity is reduced during active treatment with Fish Oil compared with placebo. Hypothesis 1c. Levels of the N-3 fatty acids, EPA and DHA, rise significantly in epileptic patients after supplementation, and are correlated with response.
|Ellsworth, G B; Lensing, S Y; Ogilvie, C B et al. (2018) A delayed dose of quadrivalent human papillomavirus vaccine demonstrates immune memory in HIV-1-infected men. Papillomavirus Res 6:11-14|
|Goldman, Noreen; Glei, Dana A; Weinstein, Maxine (2018) Declining mental health among disadvantaged Americans. Proc Natl Acad Sci U S A 115:7290-7295|
|Dean, Andy C; Morales, Angelica M; Hellemann, Gerhard et al. (2018) Cognitive deficit in methamphetamine users relative to childhood academic performance: link to cortical thickness. Neuropsychopharmacology 43:1745-1752|
|Nersesian, Paula V; Han, Hae-Ra; Yenokyan, Gayane et al. (2018) Loneliness in middle age and biomarkers of systemic inflammation: Findings from Midlife in the United States. Soc Sci Med 209:174-181|
|Glei, Dana A; Goldman, Noreen; Ryff, Carol D et al. (2018) Physical Function in U.S. Older Adults Compared With Other Populations: A Multinational Study. J Aging Health :898264318759378|
|Stephan, Yannick; Sutin, Angelina R; Bayard, Sophie et al. (2018) Personality and sleep quality: Evidence from four prospective studies. Health Psychol 37:271-281|
|Green, Shulamite A; Hernandez, Leanna M; Bowman, Hilary C et al. (2018) Sensory over-responsivity and social cognition in ASD: Effects of aversive sensory stimuli and attentional modulation on neural responses to social cues. Dev Cogn Neurosci 29:127-139|
|Green, Shulamite A; Hernandez, Leanna; Bookheimer, Susan Y et al. (2017) Reduced modulation of thalamocortical connectivity during exposure to sensory stimuli in ASD. Autism Res 10:801-809|
|Ryff, Carol D (2017) Eudaimonic well-being, inequality, and health: Recent findings and future directions. Int Rev Econ 64:159-178|
|Tsenkova, Vera K; Lee, Chioun; Boylan, Jennifer Morozink (2017) Childhood Socioeconomic Disadvantage, Occupational, Leisure-Time, and Household Physical Activity, and Diabetes in Adulthood. J Phys Act Health 14:766-772|
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