This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The incidence of type 1 diabetes is increasing, and unfortunately, rates are increasing rapidly in children under the age of six years. Serious health problems involving the blood vessels, kidneys, eyes, and nerves can develop when an individual has a long duration of diabetes, especially if the blood sugar has not been well controlled. Since the number of patients with diabetes who acquired the disease at a very young age has become significant only recently, the risk for developing these problems and the best way to evaluate for them is not well known. This study will attempt to determine if children who acquire diabetes at very young ages have less health problems than those who acquire diabetes at older ages.
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