To investigate the pathophysiology of androgen deficiency in woen with the AWS, we will assess adrenal and ovarian androgen secretion using standardized stimulation and suppression testing. Results will be compared between 20 androgen deficient women with the AIDS wasting syndrome and 20 healthy HIV-negative, age-matched controls identified from the cross sectional studies outlined above in Protocol A. IN the proposed study, we will assess the long-term effects of testosterone administration over 6 months in 60 women with AIDS wasting.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR001066-23
Application #
6409596
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
1978-02-01
Project End
2002-11-30
Budget Start
Budget End
Support Year
23
Fiscal Year
2000
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199
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