The purpose of this pilot study is to demonstrate the safety and efficacy of lovastatin in lowering the elevated levels of very long chain fatty acids(VLCFA) in patients with X-linked recessive adrenoleukodystrophy (XALD). The demonstration of the safety and efficacy of lovastatin in lowering accumulated VLCFA in vivo as proposed in this pilot study of ALD patients will pave the way for a larger Phase III clinical trial.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
3M01RR001070-24S5
Application #
6411579
Study Section
Project Start
1999-12-01
Project End
2001-03-01
Budget Start
Budget End
Support Year
24
Fiscal Year
2001
Total Cost
Indirect Cost
Name
Medical University of South Carolina
Department
Type
DUNS #
183710748
City
Charleston
State
SC
Country
United States
Zip Code
29425
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