Thrombopoietin (TPO) is a naturally occurring polypeptide that simulates the differentiation of bone marrow stem cells into megakaryocytes and stem cells. This study represents the first experience with human recombinant TPO (rhTPO) to assess its safety, tolerance, pharmacokinetics, and pharmacodynamics in subjects with solid malignancies receiving Thiotepa.

Project Start
Project End
Budget Start
Budget End
Support Year
15
Fiscal Year
1996
Total Cost
Indirect Cost
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