The specific aims of this study are: (1) to identify abnormalities of lymphocyte function, activation, or cytokine production that may predict disease activity, complications, and response to therapy in pediatric Crohn's disease; (2) to evaluate in vitro the effects of pharmacologic agents on lymphocyte function in Crohn's disease. The investigators will examine lymphocyte function and inflammatory mediators in the peripheral blood of patients with Crohn's disease as well as in control patients and disease controls.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
3M01RR002172-17S2
Application #
6220605
Study Section
Project Start
1998-12-01
Project End
1999-11-30
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
17
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Children's Hospital Boston
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02115
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