To assess the effect of individualized, circadian modulation of 5-FU chemotherapy, given with IFN, on toxicity and variance in serum 5-FU levels. To assess the maximum tolerated dose of individualized, circadian modulated 5-FU chemotherapy given with IFN. To assess the anti-tumor activity of this drug combination given in this manner.

Project Start
Project End
Budget Start
Budget End
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
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