To determine whether early intervention by antigen based therpaies in non-diabetic relatives of persons with IDDM can delay their development of IDDM as a clinical disease.
Other aims i n this study will include 1) to determine the influence of these interventions of beta cell function; 2) to determine the influence of these interventions on humoral and cellular immune responses directed at pancreatic beta cells and their antigens; 3)to improve predicability of IDDM amond relatives;4)identify factors that influence disease progression.
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