This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. To establish oral THC as a discriminative stimulus and characterize its effects on behavior and cognition. It is hypothesized that THC will function as a discriminative stimulus and produce other effects typically seen following cannabis administration. To determine if the effects of oral THC in humans can also be attributed to indirect involvement of the opioid, GABA and DA systems. It is hypothesized that the opioid agonist hydromorphone and GABA modulator triazolam will partially substitue for THC and will have similar effects to THC on most expermental measures. In contrast it is hypothesized that the indirect DA agonist methylphenidate will not share discriminative-stimulus effects with THC and will have opposite effects on most experimental measures.
| Reed, Rebecca G; Greenberg, Richard N; Segerstrom, Suzanne C (2017) Cytomegalovirus serostatus, inflammation, and antibody response to influenza vaccination in older adults: The moderating effect of beta blockade. Brain Behav Immun 61:14-20 |
| Abshire, Demetrius A; Moser, Debra K; Clasey, Jody L et al. (2017) Body Composition and Bone Mineral Density in Patients With Heart Failure. West J Nurs Res 39:582-599 |
| Ahmed, Zuhayer; Hafez, M A; Bari, M A et al. (2016) Pattern of anti-diabetic drugs prescribed in a tertiary care hospital of Bangladesh. Int J Basic Clin Pharmacol 5:6-12 |
| Harrison, Jordan M; Jung, Miyeon; Lennie, Terry A et al. (2016) Refusal to participate in heart failure studies: do age and gender matter? J Clin Nurs 25:983-91 |
| Nagarajan, Radhakrishnan; Miller, Craig S; Dawson 3rd, Dolph et al. (2015) Patient-Specific Variations in Biomarkers across Gingivitis and Periodontitis. PLoS One 10:e0136792 |
| Ebersole, Jeffrey L; Nagarajan, Radhakrishnan; Akers, David et al. (2015) Targeted salivary biomarkers for discrimination of periodontal health and disease(s). Front Cell Infect Microbiol 5:62 |
| Ewen, Heidi H; Chahal, Jasleen K; Fenster, Emily S (2015) A portrait of resilience in caregiving. Res Gerontol Nurs 8:29-38 |
| Alhurani, Abdullah S; Dekker, Rebecca L; Abed, Mona A et al. (2015) The association of co-morbid symptoms of depression and anxiety with all-cause mortality and cardiac rehospitalization in patients with heart failure. Psychosomatics 56:371-80 |
| Biddle, Martha J; Lennie, Terry A; Bricker, Gregory V et al. (2015) Lycopene dietary intervention: a pilot study in patients with heart failure. J Cardiovasc Nurs 30:205-12 |
| Martin, Catherine Anne; Lile, Joshua; Guenthner, Greg et al. (2014) Behavioral effects of modafinil and nicotine, alone and in combination, in tobacco-deprived young adult smokers. J Clin Psychopharmacol 34:278-81 |
Showing the most recent 10 out of 232 publications
