This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.Rituximab is a genetically engineered chimeric, murine/human monoclonal antibody. Directed against the CD20 antigen on B-cells. Promotes B-cell lysis, down regulation, apoptosis and down regulation.
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