This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of the study is to determine whether inflammation, an irritation of the blood vessel wall and the inability of cells to properly use glucose for energy promote the development of atherosclerosis and worsen symptoms of muscular leg pain with walking because the blood supply to these muscles is inadequate.
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