Abstract

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to test whether a lack of light perception causes disruption of circadian rhythms and whether there are differences in the timing of the internal body clock between individuals with and without light perception. The data from the study may lead to a better understanding of sleep disruptions and circadian rhythm disorders in blind and sighted people, and may help to develop a potential therapy for blind people so that they stay adapted to the 24-hour day.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR002635-22
Application #
7379264
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
2006-04-01
Project End
2007-03-31
Budget Start
2006-04-01
Budget End
2007-03-31
Support Year
22
Fiscal Year
2006
Total Cost
$549
Indirect Cost

  Institution

Name
Brigham and Women's Hospital
Department
Type
DUNS #
030811269
City
Boston
State
MA
Country
United States
Zip Code

  Publications

Scheuermaier, Karine; Münch, Mirjam; Ronda, Joseph M et al. (2018) Improved cognitive morning performance in healthy older adults following blue-enriched light exposure on the previous evening. Behav Brain Res 348:267-275
Mukhopadhyay, Sagori; Puopolo, Karen M (2017) Clinical and Microbiologic Characteristics of Early-onset Sepsis Among Very Low Birth Weight Infants: Opportunities for Antibiotic Stewardship. Pediatr Infect Dis J 36:477-481
Hundemer, Gregory L; Baudrand, Rene; Brown, Jenifer M et al. (2017) Renin Phenotypes Characterize Vascular Disease, Autonomous Aldosteronism, and Mineralocorticoid Receptor Activity. J Clin Endocrinol Metab 102:1835-1843
Bullock, B; Murray, G; Anderson, J L et al. (2017) Constraint is associated with earlier circadian phase and morningness: Confirmation of relationships between personality and circadian phase using a constant routine protocol. Pers Individ Dif 104:69-74
Klerman, Elizabeth B; Wang, Wei; Phillips, Andrew J K et al. (2017) Statistics for Sleep and Biological Rhythms Research. J Biol Rhythms 32:18-25
Rachmin, Inbal; O'Meara, Caitlin C; Ricci-Blair, Elisabeth M et al. (2017) Soluble interleukin-13r?1: a circulating regulator of glucose. Am J Physiol Endocrinol Metab 313:E663-E671
Buxton, Orfeu M; Pavlova, Milena K; O'Connor, Shawn P et al. (2017) Lack of change in glucose metabolism in eszopiclone-treated primary insomnia patients. Nat Sci Sleep 9:187-198
Juraschek, Stephen P; Miller 3rd, Edgar R; Weaver, Connie M et al. (2017) Effects of Sodium Reduction and the DASH Diet in Relation to Baseline Blood Pressure. J Am Coll Cardiol 70:2841-2848
Bray, G A; Ryan, D H; Johnson, W et al. (2017) Markers of dietary protein intake are associated with successful weight loss in the POUNDS Lost trial. Clin Obes 7:166-175
Bianchi, Matt T; Phillips, Andrew J K; Wang, Wei et al. (2017) Statistics for Sleep and Biological Rhythms Research. J Biol Rhythms 32:7-17

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