The purpose of this study is to determine the effects of a walking exercise program on management of fatigue during breast cancer treatment. The study is a randomized, controlled clinical trial design, stratified by type of medical treatment: radiotherapy, adjuvant chemotherapy, or combined modalities. Four university teaching hospitals with National Cancer Institute designed Cancer Centers and one community cancer center comprise the clinical research settings. The sample consists of newly diagnosed Stage I-III breast cancer patients who have completed surgical treatment and are beginning primary radiotherapy or adjuvant cytotoxic chemotherapy or combinations of both. Following random assignment, subjects in the exercise group will be prescribed an individualized, self-paced, home-based walking exercise program that they will maintain throughout their cancer treatment. Subjects in the control group will receive the usual care given during breast cancer treatment (no prescribed walking program). Symptoms and response to treatment will be assessed at the beginning, middle and end of either therapy. Groups will be compared by statistical analysis. The independent variable is participation in a walking exercise program. The primary dependent variable is fatigue level; additional variables are physical functioning, emotional distress, difficulty sleeping, weight gain, and quality of life. The out-of-pocket costs of cancer care and its relationship to unmanaged symptoms will also be investigated.

Project Start
1999-12-01
Project End
2000-11-30
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
15
Fiscal Year
2000
Total Cost
$65,169
Indirect Cost
Name
Johns Hopkins University
Department
Type
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
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