This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Pressure sores are a common, costly, and painful condition with a prevalence ranging from 3-14% among patients in acute care hospitals. Malnutrition associated with decreased food intake, low dietary protein and recent weight loss has been associated with the development of pressure sores. It is not known whether replenishment of energy expenditures leads to improved treatment of pressure sores. The primary goal of this project is to conduct a metabolic assessment in patients with pressure ulcers by measuring resting energy expenditure in patients with Stage III and IV sacral pressure ulcers. In addition, efforts will be made to determine the accuracy of current prediction equations of energy expenditure, the relationship between resting energy expenditure and physiologic parameters, and the energy balance in patients with sacral pressure ulcers.
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