This research study is to compare the effectiveness of a new drug, Uracil/Ftorafur (UFT) when given with the drug leucovorin (LV), to a standard treatment using a combination of the drugs 5-fluorouracil (5-FU) and LV in patients who have had a resection of their colon cancer. In previous studies where doctors thought they had removed all the colon cancer, a significant number of patients had a return of their cancer at a later time. Studies have shown that using chemotherapy after surgery can decrease the chance of cancer returning and can prolong the survival of the patients with tumors that invade through the bowel wall or that involve the lymph nodes in the area. The combination of two chemotherapy drugs, LV and 5-FU, has been shown to be effective for the treatment of colon cancer. UFT is a new investigational drug that has been found effective in their treating patients with advanced colon cancer.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
2M01RR005096-10A1
Application #
6122165
Study Section
Project Start
1999-07-19
Project End
1999-11-30
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
10
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Tulane University
Department
Type
DUNS #
City
New Orleans
State
LA
Country
United States
Zip Code
70118
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