The Longitudinal Study of Ocular Complication of AIDS (LSOCA) is a multicenter, prospective, observational study of patients with AIDS. Patients with a diagnosis of AIDS according to the 1993 CDC criteria, with or without ocular complications, will be enrolled over a 4 year period. The objectives of the study are: 1) to monitor secular trends in the incidence of ocular complication of AIDS; 2) to determine the effect of HAART-induced changes in immune status on the incidence and course of ocular complications of AIDS; 3) to determine the characteristics of patients that place them at high risk for ocular complications; and 4) to evaluate the effects of treatments of CMV retinitis and other ocular complications on visual function, quality of life, and survival. Other outcomes of interest include incidence of extra-ocular CMV disease, sequelae of AIDS-related eye disease, visual function, quality of life, and incidence of complications of therapies for ocular complications.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR005096-11
Application #
6411320
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
1990-01-14
Project End
2001-11-30
Budget Start
Budget End
Support Year
11
Fiscal Year
2000
Total Cost
Indirect Cost
Name
Tulane University
Department
Type
DUNS #
City
New Orleans
State
LA
Country
United States
Zip Code
70118
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