Insulin Requirements in Adolescent Diabetics

Santiago, Julio V.

Abstract

It has been found that diabetics develop marked increase in insulin requirements during adolescence. This """"""""insulin resistance"""""""" in adolescence is being studied to determine if insulin receptor changes or excessive insulin degradation can explain the phenomenon. One possible mechanisms for the """"""""insulin resistance"""""""" is an increase in certain growth factors such as somatomedin C during puberty.

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Center for Research Resources (NCRR)
• Type: General Clinical Research Centers Program (M01)
• Project #: 5M01RR006021-02
• Application #: 3871895
• Support Year: 2
• Fiscal Year: 1991

Institution

• Name: Washington University
• DUNS #: 062761671
• City: Saint Louis
• State: MO
• Country: United States
• Zip Code: 63130

Publications

Thompson, S J; Auslander, W F; White, N H (2001) Comparison of single-mother and two-parent families on metabolic control of children with diabetes. Diabetes Care 24:234-8

Thompson, S J; Auslander, W F; White, N H (2001) Influence of family structure on health among youths with diabetes. Health Soc Work 26:7-14

Arfken, C L; Reno, P L; Santiago, J V et al. (1998) Development of proliferative diabetic retinopathy in African-Americans and whites with type 1 diabetes. Diabetes Care 21:792-5

Auslander, W F; Thompson, S; Dreitzer, D et al. (1997) Disparity in glycemic control and adherence between African-American and Caucasian youths with diabetes. Family and community contexts. Diabetes Care 20:1569-75

Reno, P L; Arfken, C L; Heins, J M et al. (1997) Factors that influence the decision to receive treatment for proliferative diabetic retinopathy. Diabetes Educ 23:653-5

Auslander, W F; Thompson, S J; Dreitzer, D et al. (1997) Mothers' satisfaction with medical care: perceptions of racism, family stress, and medical outcomes in children with diabetes. Health Soc Work 22:190-9

Arfken, C L; Schmidt, L E; McGill, J B et al. (1996) Major decrements in glycated hemoglobin levels between 1978 and 1989 in patients with insulin-dependent diabetes mellitus. J Diabetes Complications 10:12-7

Arfken, C L; Salicrup, A E; Meuer, S M et al. (1994) Retinopathy in African Americans and whites with insulin-dependent diabetes mellitus. Arch Intern Med 154:2597-602

Bonilla-Felix, M; Villegas-Medina, O; Vehaskari, V M (1994) Renal acidification in children with idiopathic hypercalciuria. J Pediatr 124:529-34

Noel, G J; Katz, S L; Edelson, P J (1991) The role of C3 in mediating binding and ingestion of group B streptococcus serotype III by murine macrophages. Pediatr Res 30:118-23