The primary goals of this study are: 1) To document, on the basis of circulating hormone levels and menstrual history, a pre-menopausal woman's menstrual phase at the time of her primary breast cancer surgery (follicular vs. luteal); 2) To study any association between menstrual cycle phase (follicular vs. luteal) at breast cancer surgery and disease-free survival at 5 years; 3) To compare these breast cancer patient's menstrual cycle data, as determined by hormone levels and the study-specific menstrual cycle history with what is recorded in the general written record; and 4) To estimate the disease-free survival distribution of those women who undergo a two-stage procedure at which cancer is found at both stages and the procedure is not confirmed to one menstrual cycle phase.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR006192-07
Application #
6412346
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
1993-12-15
Project End
2003-11-30
Budget Start
Budget End
Support Year
7
Fiscal Year
2000
Total Cost
Indirect Cost
Name
University of Connecticut
Department
Type
DUNS #
City
Farmington
State
CT
Country
United States
Zip Code
06030
Lieberman, Richard; Kranzler, Henry R; Levine, Eric S et al. (2018) Examining the effects of alcohol on GABAA receptor mRNA expression and function in neural cultures generated from control and alcohol dependent donor induced pluripotent stem cells. Alcohol 66:45-53
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