This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.The specific hypotheses to be tested are 1) Implementation of Voucher Based Reinforcement Therapy (VBRT) for youth with Cannabis Use Disorder is feasible and acceptable for both youths and therapists; 2) VBRT for youth produces a reduction of cannabis use during and at the completion of treatment; and 3) VBRT reinforcement for youth enhances a superior reduction of cannabis use relative to the non-reinforcement control condition. The proposed trial follows the guidelines for a preliminary Stage I study developed by the National Institute of Drug Abuse (NIDA) (Rounsaville et al., 2001). The goals of a Stage I project are 1) to determine whether or not a Stage II project is indicated for the therapy examined in a Stage I project, and 2) if so, provide the necessary procedures, manuals, measures, and data needed to support a Stage II application (e.g., effect size estimates). Decision on appropriateness of Stage II project implies that the data generated supports the feasibility and clinical utility of the therapy examined for that condition, and/or behavior that it is designed to treat.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR006192-14
Application #
7607655
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
2007-04-01
Project End
2008-03-31
Budget Start
2007-04-01
Budget End
2008-03-31
Support Year
14
Fiscal Year
2007
Total Cost
$16,939
Indirect Cost
Name
University of Connecticut
Department
Type
Schools of Medicine
DUNS #
022254226
City
Farmington
State
CT
Country
United States
Zip Code
Lieberman, Richard; Kranzler, Henry R; Levine, Eric S et al. (2018) Examining the effects of alcohol on GABAA receptor mRNA expression and function in neural cultures generated from control and alcohol dependent donor induced pluripotent stem cells. Alcohol 66:45-53
Usmani, Saad; Choquette, Linda; Bona, Robert et al. (2018) Transient bacteremia induced by dental cleaning is not associated with infection of central venous catheters in patients with cancer. Oral Surg Oral Med Oral Pathol Oral Radiol 125:286-294
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Lieberman, Richard; Kranzler, Henry R; Levine, Eric S et al. (2017) Examining FKBP5 mRNA expression in human iPSC-derived neural cells. Psychiatry Res 247:172-181
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Lieberman, Richard; Armeli, Stephen; Scott, Denise M et al. (2016) FKBP5 genotype interacts with early life trauma to predict heavy drinking in college students. Am J Med Genet B Neuropsychiatr Genet 171:879-87
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