This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.Aging is associated with sarcopenia (loss of muscle mass and strength) and impaired physical function (i.e. balance and walking speed). As such, interventions aimed at increasing lean body mass and muscle strength in the elderly will be beneficial in improving physical function and independence in these populations. Several studies have shown that low-magnitude, high-frequency vibrations serve as a mechanical stimulus that is anabolic to both bone and muscle. For example, it has been reported that one year of low-magnitude, high-frequency mechanical stimuli can increase bone and muscle mass in young adult women and inhibit bone loss in middle-aged post-menopausal women. Thus, it is possible that a whole body vibration exercise intervention may improve strength and physical function in the elderly.
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