Human Gh/Short Stature Due to Intra-Uterine Growth Retardation

Chernausek, Steven D.

Abstract

This study is a clinical trial examining the use of rhGH as a growth-promoting agent in short stature due to intra-uterine growth retardation. Ten children aged 3-10 with stature > 2 SD's below the mean were treated with rhGH and followed for 4 years, assessing nutritional components, anthropometrics, body composition, and growth patterns. These variables are being analyzed along with serum IGF-1, IGF-BP3, and GHBP.

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Center for Research Resources (NCRR)
• Type: General Clinical Research Centers Program (M01)
• Project #: 5M01RR008084-02
• Application #: 3744991
• Support Year: 2
• Fiscal Year: 1995

Institution

• Name: Cincinnati Children's Hospital Medical Center
• DUNS #: 071284913
• City: Cincinnati
• State: OH
• Country: United States
• Zip Code: 45229

Publications

Natarajan, Girija; Shankaran, Seetha; Laptook, Abbot R et al. (2018) Association between sedation-analgesia and neurodevelopment outcomes in neonatal hypoxic-ischemic encephalopathy. J Perinatol 38:1060-1067

Askie, Lisa M; Darlow, Brian A; Finer, Neil et al. (2018) Association Between Oxygen Saturation Targeting and Death or Disability in Extremely Preterm Infants in the Neonatal Oxygenation Prospective Meta-analysis Collaboration. JAMA 319:2190-2201

DiFrancesco, Mark W; Shamsuzzaman, Abu; McConnell, Keith B et al. (2018) Age-related changes in baroreflex sensitivity and cardiac autonomic tone in children mirrored by regional brain gray matter volume trajectories. Pediatr Res 83:498-505

Autmizguine, Julie; Tan, Sylvia; Cohen-Wolkowiez, Michael et al. (2018) Antifungal Susceptibility and Clinical Outcome in Neonatal Candidiasis. Pediatr Infect Dis J 37:923-929

Jilling, Tamas; Ambalavanan, Namasivayam; Cotten, C Michael et al. (2018) Surgical necrotizing enterocolitis in extremely premature neonates is associated with genetic variations in an intergenic region of chromosome 8. Pediatr Res 83:943-953

Hahn, Andrew D; Higano, Nara S; Walkup, Laura L et al. (2017) Pulmonary MRI of neonates in the intensive care unit using 3D ultrashort echo time and a small footprint MRI system. J Magn Reson Imaging 45:463-471

Kingery, Kathleen M; Narad, Megan E; Taylor, H Gerry et al. (2017) Do Children Who Sustain Traumatic Brain Injury in Early Childhood Need and Receive Academic Services 7 Years After Injury? J Dev Behav Pediatr 38:728-735

Glauser, Tracy A; Holland, Katherine; O'Brien, Valerie P et al. (2017) Pharmacogenetics of antiepileptic drug efficacy in childhood absence epilepsy. Ann Neurol 81:444-453

Durber, Chelsea M; Yeates, Keith Owen; Taylor, H Gerry et al. (2017) The family environment predicts long-term academic achievement and classroom behavior following traumatic brain injury in early childhood. Neuropsychology 31:499-507

Hung, Anna H; Cassedy, Amy; Schultz, Hanna M et al. (2017) Predictors of Long-Term Victimization After Early Pediatric Traumatic Brain Injury. J Dev Behav Pediatr 38:49-57