This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Biologic and Psychosocial variables associated with the development of acute stress disorder (ASD) and posttraumatic stress disorder (PTSD) in patients being treated for acute trauma at Howard University Hospital (level 1 trauma care center) will be measured during this study.
Specific Aims : (1) Specifically, heart rate, heart rate variability; plasma NE, NPY, and cortisol/salivary cortisol will be measured in patients following an acute trauma. (2) These patients will be followed prostpectively at 1 week, at 1, 4, and 8 months, and one year for similar measures and the development of PTSD. (3) Associated risk and protective factors will be evaluated prospectively as well. Methods: Patients arriving at the emergency room at Howard University Hospital will be assessed medically and psychologically, including heart rate as part of their initial assessment, asked to give salivary, urine and plasma samples. Patients will have subsequent interviews assessing PTSD and other psychiatric conditions. Socio-demographic data will be collected as well (age, gender, eductaion, marital status, occupational status, poverty status, and ethnicity). Participants will also be assessed for medical problems and alcohol/substance abuse.
Showing the most recent 10 out of 205 publications
