This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.The goal of this pilot study is to examine the cardiovascular and sympathetic responses to venous vascular distention in skeletal muscles. It is postulated that peripheral vascular distention may evoke sympathetic activation, inducing a pressor response (Increased B.P. and H.R.) in humans. Venous distention will be produced by intravenous saline infusion under various conditions and the muscle sympathetic neural activity (MSNA) will be reflected in B.P. and H.R. changes. The hypothesis is that peripheral venous distention will evoke an increase in MSNA.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR010732-14
Application #
7718836
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
2008-04-01
Project End
2009-03-31
Budget Start
2008-04-01
Budget End
2009-03-31
Support Year
14
Fiscal Year
2008
Total Cost
$2,839
Indirect Cost
Name
Pennsylvania State University
Department
Type
Schools of Medicine
DUNS #
129348186
City
Hershey
State
PA
Country
United States
Zip Code
17033
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