This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Prevalence of overweight/obesity is a major concern that speaks to the need for effective weight-loss interventions that can be followed long-term. The 2005 Dietary Guidelines provide food-group recommendations to achieve nutrient adequacy. The purpose of the study is to develop a weight-loss program using the 2005 Dietary Guidelines at the extremes of dietary fat recommended (20% and 35% energy). The education program will consist of 28 lessons, focusing on nutrition and physical activity. It will be tested in a year-long weight-loss intervention (4 months of weight-loss, 8 months of weight-maintenance) in 100 overweight/obese pre-menopausal women. Education sessions will be held weekly for 4 months, biweekly for the next 4 months, and monthly for the last four months. Subjects will attend 2 supervised workouts weekly. The primary endpoint is weight loss;other endpoints include body composition, lipids and lipoproteins, C-reactive protein, glucose, insulin, quality of life, eating competence, appetite, and diet satisfaction. It is hypothesized that both diets will elicit weight-loss;however, 'profiles'defined by quality of life, eating competence, diet satisfaction, and appetite will determine which diet is better for different people. It is hypothesized that adherence will be greater in the moderate-fat group while caloric reduction will be more successful in the lower-fat group.
| Lieberman, Jay L; DE Souza, Mary Jane; Wagstaff, David A et al. (2018) Menstrual Disruption with Exercise Is Not Linked to an Energy Availability Threshold. Med Sci Sports Exerc 50:551-561 |
| Zhang, Lijun; Wang, Ming; Sterling, Nicholas W et al. (2018) Cortical Thinning and Cognitive Impairment in Parkinson's Disease without Dementia. IEEE/ACM Trans Comput Biol Bioinform 15:570-580 |
| Rossi, Alexander; Berger, Kristin; Chen, Honglei et al. (2018) Projection of the prevalence of Parkinson's disease in the coming decades: Revisited. Mov Disord 33:156-159 |
| Lee, Soomi; Martire, Lynn M; Damaske, Sarah A et al. (2018) Covariation in couples' nightly sleep and gender differences. Sleep Health 4:201-208 |
| Almeida, David M; Lee, Soomi; Walter, Kimberly N et al. (2018) The effects of a workplace intervention on employees' cortisol awakening response. Community Work Fam 21:151-167 |
| Liu, Guodong; Sterling, Nicholas W; Kong, Lan et al. (2017) Statins may facilitate Parkinson's disease: Insight gained from a large, national claims database. Mov Disord 32:913-917 |
| Sterling, Nicholas W; Du, Guangwei; Lewis, Mechelle M et al. (2017) Cortical gray and subcortical white matter associations in Parkinson's disease. Neurobiol Aging 49:100-108 |
| Berryman, Claire E; Fleming, Jennifer A; Kris-Etherton, Penny M (2017) Inclusion of Almonds in a Cholesterol-Lowering Diet Improves Plasma HDL Subspecies and Cholesterol Efflux to Serum in Normal-Weight Individuals with Elevated LDL Cholesterol. J Nutr 147:1517-1523 |
| Calhoun, Susan L; Fernandez-Mendoza, Julio; Vgontzas, Alexandros N et al. (2017) Behavioral Profiles Associated with Objective Sleep Duration in Young Children with Insomnia Symptoms. J Abnorm Child Psychol 45:337-344 |
| Berger, Paige K; Hohman, Emily E; Marini, Michele E et al. (2016) Girls' picky eating in childhood is associated with normal weight status from ages 5 to 15 y. Am J Clin Nutr 104:1577-1582 |
Showing the most recent 10 out of 645 publications
